dysplasia, dGEMRIC has been shown to correlate with patient symptoms and performed on the same 1.5T scanner (Magnetom Avanto, Siemens Erlangen).

Background Lesions in the meniscus are risk factors for developing knee osteoarthritis (OA), not least because of the role of the meniscus in the pathological progression of OA. Delayed gadolinium enhanced MRI of cartilage (dGEMRIC) has extensively been used to identify pre-radiographic cartilage changes in OA. In contrast, its counterpart with regard to examination of the meniscus, gadolinium

dGEMRIC images were analyzed by an experienced musculoskeletal radiologist using the syngoMaplt software (Siemens). The dGEMRIC index was analyzed on seven di erent articular facets: the medial and lateral femoral condyle, femoral trochlea, medial and lateral tibial condyle and both patellar facets, before dGEMRIC, on demographic and KL grade data or on knee alignment data were excluded from the analysis (figure 1). MR imaging protocol Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG, Erlangen, Germany) were used at three of the seven study sites, two sites used Signa Excite/Genesis 3.0 T MRI long-bore MR examinations were performed on a Siemens 1.5 T system (Magnetom Avanto, Siemens, Erlangen, Germany) and a body matrix phased array coil. The dGEMRIC scans were obtained after a double dose (0.4 mL/kg) intravenous injection of FDA approved contrast agent Magnevist (Gd-DTPA2; Berlex Laboratories, Wayne, NJ). Patients were The MRI imaging was performed using a 1.5 T Siemens Avanto MRI machine (Siemens Healthcare GmbH, Erlangen, Germany). The patients were examined using a standard knee MRI protocol [13] that was developed and used at Oslo University Hospital and included T2 mapping and a dGEMRIC [14].

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Pre Longitudinal assessment of femoral knee cartilage quality using contrast enhanced MRI (dGEMRIC) in patients with anterior cruciate ligament injury – comparison with asymptomatic volunteers In this observational longitudinal study we estimate knee joint cartilage glycosaminoglycan (GAG) content, in patients with an acute anterior cruciate ligament (ACL) injury, with or without a concomitant 2018-05-09 · T2 and dGEMRIC index change during the 12-month follow-up and P value for linearity in relation to LTPA level are given in Table 3. In knee cartilage regions, there was a statistically significant linear relationship showing that dGEMRIC index in posterior ROI of the lateral ( P = 0.003) and medial ( P = 0.006) femoral cartilage increased with higher LTPA level during 12-month period. Elektrifizierung, Automatisierung und Digitalisierung fordern innovative Lösungen: Entdecken Sie Siemens als starken Partner, Technologieführer und spannenden Arbeitgeber. Siemens er verdens største batterileverandør og vores energilagringssystemer bygger på anerkendte teknologier, der sikrer effektiv lagring og anvendelse af vedvarende energi til den lavest mulige pris. Vi leverer energilagringsløsninger til store såvel som til mindre anlæg. Thirty-five hips in 35 patients presenting with varying radiographic evidence of arthritis in the hip were imaged using a 3D isotropic fast T1 mapping dGEMRIC sequence (TR 15 msec, TE 3.27 msec, flip angles of 4.1 and 23.5 deg., Matrix size 192/192, 16 cm FoV, voxel size 0.8 x 0.8 x 0.8 mm) and a previously validated fast T1 mapping dGEMRIC sequence (voxel size 0.6 x 0.6 x 4 mm) for comparison. Jul 19, 2020 cartilage (dGEMRIC) index over 2 years as a measure of cartilage Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG,. Erlangen  Oct 22, 2013 Knee cartilage assessment with MRI (dGEMRIC) and subjective knee with a dedicated knee coil (Magnetom Vision; Siemens Medical.

onance imaging of cartilage (dGEMRIC) by means of histological analyses in the assessment of MRI was performed in a 3 T system (Magnetom Trio, Siemens.

Objective To determine the association between changes in the delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) index over 2 years as a measure of cartilage proteoglycan concentration, with changes in cartilage thickness in the medial tibiofemoral compartment of knees in middle-aged women. Methods One hundred and forty-eight women (one knee for each subject) aged ≥40 years were included

a) Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC*) GAG are important to the cartilage tissue’s The dGEMRIC Index was 14.4% lower in the medial index compartment (374 61 ms, mean SD) than in the lateral reference compartment (437 59 ms, mean SD) (P<0.001). The dGEMRIC Index of the medial diseased compartment correlated positively with both knee flexor (r¼0.50, P¼0.001) and knee extensor Interestingly, when we compared results from our previously published article assessing the one year effect after intra-articular injection of autologous microfragmented adipose tissue, where out of 331 dGEMRIC measurements, 175 measurements (82.6%) were showing changes with a greater magnitude than 15%, while the remaining 37 dGEMRIC measurements (17.5%) were showing relevant decrease, it Methods: Twenty-seven participants (age = 28.8 ± 8.6 yrs; BMI = 24.2 ± 2.3 kg m −2; 44% females) diagnosed with FAI syndrome (cam-, pincer- or combined-type FAI morphology concurrent with symptoms) underwent hip MRI with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in one of two 3T scanners (Siemens Prisma, Siemens Skyra). The using 3D dGEMRIC at two different doses of the contrast agent Gd-DTPA2-. Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight).

using 3D dGEMRIC at two different doses of the contrast agent Gd-DTPA2-. Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight). The relaxation time (T 1) and relaxation rate (R 1 =1/T

Background Lesions in the meniscus are risk factors for developing knee osteoarthritis (OA), not least because of the role of the meniscus in the pathological progression of OA. Delayed gadolinium enhanced MRI of cartilage (dGEMRIC) has extensively been used to identify pre-radiographic cartilage changes in OA. In contrast, its counterpart with regard to examination of the meniscus, gadolinium The majority of dGEMRIC studies have been in the knee and hip, although there are a number of reports of dGEMRIC applied to the finger joints [12, 50–52] and ankle .

This could aid in patient-specific diagnosis of FAI, preoperative patient selection, and surgical decision making to identify patients with cartilage damage who are at risk for inferior outcomes after hip arthroscopy. Methods: Twenty-seven participants (age = 28.8 ± 8.6 yrs; BMI = 24.2 ± 2.3 kg m −2; 44% females) diagnosed with FAI syndrome (cam-, pincer- or combined-type FAI morphology concurrent with symptoms) underwent hip MRI with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in one of two 3T scanners (Siemens Prisma, Siemens Skyra).
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Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight).

Th This definition approximates grade 2 knee OA based on the Kellgren and Lawrence scale 36 .
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Furthermore, we defined dGEMRIC and T map- (Siemens Healthcare), which provides the protocols and inline cal- ping reference values for healthy and diseased cartilage of culation of parametric maps of T and T properties of the imaged 1 2 the wrist at 3T. tissue and …

Thirty-five hips in 35 patients presenting with varying radiographic evidence of arthritis in the hip were imaged using a 3D isotropic fast T1 mapping dGEMRIC sequence (TR 15 msec, TE 3.27 msec, flip angles of 4.1 and 23.5 deg., Matrix size 192/192, 16 cm FoV, voxel size 0.8 x 0.8 x 0.8 mm) and a previously validated fast T1 mapping dGEMRIC sequence (voxel size 0.6 x 0.6 x 4 mm) for comparison. Jul 19, 2020 cartilage (dGEMRIC) index over 2 years as a measure of cartilage Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG,. Erlangen  Oct 22, 2013 Knee cartilage assessment with MRI (dGEMRIC) and subjective knee with a dedicated knee coil (Magnetom Vision; Siemens Medical.

17 patients with active PsA were evaluated by high-resolution clinical standard morphological and dGEMRIC sequences using a 3T MRI scanner (Magnetom Skyra, Siemens) and a dedicated 16-channel hand coil. Images were analyzed by two independent raters for dGEMRIC indices, PsA MRI scores (PsAMRIS), and total cartilage thickness (TCT).

Siemens Magnetom Trio 3.0T magnets 2016-10-05 dGEMRIC, on demographic and KL grade data or on knee alignment data were excluded from the analysis (figure 1). MR imaging protocol Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG, Erlangen, Germany) were used at three of the seven study sites, two sites used Signa Excite/Genesis 3.0 T … Interestingly, when we compared results from our previously published article assessing the one year effect after intra-articular injection of autologous microfragmented adipose tissue, where out of 331 dGEMRIC measurements, 175 measurements (82.6%) were showing changes with a greater magnitude than 15%, while the remaining 37 dGEMRIC measurements (17.5%) were showing relevant decrease, it Objective: To prospectively compare chemical-exchange saturation-transfer (CEST) with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and T2 mapping to assess the biochemical cartilage properties of the knee. Method: Sixty-nine subjects were prospectively included (median age, 42 years; male/female = 32/37) in three cohorts: 10 healthy volunteers, 40 patients with clinically suspected This definition approximates grade 2 knee OA based on the Kellgren and Lawrence scale 36 . MRISubjects were investigated with dGEMRIC 20.6 years (mean; range 18e23) after the injury, using a standard 1.5 T MRI system with a dedicated knee coil (Magnetom Vision; Siemens Medical Solutions, Erlangen, Germany). MRI with dGEMRIC was more sensitive than morphological MRI, and lower dGEMRIC values were found for clock positions with impingement as detected on 3D-CT. This could aid in patient-specific diagnosis of FAI, preoperative patient selection, and surgical decision making to identify patients with cartilage damage who are at risk for inferior outcomes after hip arthroscopy. Methods: Twenty-seven participants (age = 28.8 ± 8.6 yrs; BMI = 24.2 ± 2.3 kg m −2; 44% females) diagnosed with FAI syndrome (cam-, pincer- or combined-type FAI morphology concurrent with symptoms) underwent hip MRI with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in one of two 3T scanners (Siemens Prisma, Siemens Skyra).

Furthermore, we defined dGEMRIC and T map- (Siemens Healthcare), which provides the protocols and inline cal- ping reference values for healthy and diseased cartilage of culation of parametric maps of T and T properties of the imaged 1 2 the wrist at 3T. tissue and automatically generates parametric color-coded maps. MR IMAGINGThe MR images were performed on a 1.5T magnet (Symphony; Siemens, Erlangen, Germany) using a quadrature knee coil (Siemens, Erlangen, Germany). Since we intended to perform the dGEMRIC analyses on the femoral and tibial articular cartilage from a single, 3 mm-thick slice through the median plane of the medial femoral condyle (Fig. 1 ROC-analysis demonstrated non-significant differences of T2 mapping vs CEST (P = 0.14), CEST vs dGEMRIC (P = 0.89), and T2 mapping vs dGEMRIC (P = 0.12). Conclusion: CEST is able to detect normal and damaged cartilage and is non-inferior in distinguishing both when compared to dGEMRIC and T2 mapping.